Density Gradient Centrifugation Compromises Bone Marrow Mononuclear Cell Yield
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چکیده
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Density Gradient Centrifugation Compromises Bone Marrow Mononuclear Cell Yield
Bone marrow mononuclear cells (BMNCs) are widely used in regenerative medicine, but recent data suggests that the isolation of BMNCs by commonly used Ficoll-Paque density gradient centrifugation (DGC) causes significant cell loss and influences graft function. The objective of this study was to determine in an animal study whether and how Ficoll-Paque DGC affects the yield and composition of BM...
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This open‐access article is published and distributed under the Creative Commons Attribution ‐ NonCommercial ‐ No Derivatives License (http://creativecommons.org/licenses/by‐nc‐nd/3.0/), which permits the noncommercial use, distribution, and reproduction of the article in any medium, provided the original author and source are credited. You may not alter, transform, or build upon this article w...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2012
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0050293